Hi Paul, I'm glad to assist you. Yes, the DiabloSport inTune i3 Series Tuner (part number 8200) can deactivate the Displacement on Demand (DOD) system on your 2006 Chevrolet Impala SS. The 2006 Impala SS is equipped with a 5.3L V8 engine that utilizes the DOD (also known as Active Fuel Management or AFM) system to deactivate certain cylinders under light load for better fuel economy (it is still best to call Diablo Sport to confirm the details you were asking). Grab our price-cut promo and click the link below to buy it today. Happy shopping! https://www.carparts.com/tuner/diablo-sport/dbs8200?can=cpje1043_CSQA_20250106

Hi Paul, I'm glad to assist you. The tuner adjusts options like timing, fueling, idle, speed limiters, rev limiters, tire size, and gear ratios, and it reads and clears DTC. You get a performance tuning upgrade that makes your throttle more responsive, optimizes drivability, improves fuel economy potential, and increases horsepower and torque. The inTune i3 programmer is pre-loaded with dyno-tested performance programs designed specifically for your ride. If you decide to order, grab our price-cut promo and click the link below to buy it today. Happy shopping! https://www.carparts.com/tuner/diablo-sport/dbs8200?can=cpje1043_CSQA_20241130

Hi Roland, thanks for initiating contact. Yes, this tuner (model 8200) can disable Active Fuel Management (AFM) on vehicles, including the 2006 GMC Envoy Denali with the 5.3L V8 engine. Users have reported successfully using the tuner to turn off AFM/DFM (Dynamic Fuel Management) features, which allows the engine to operate solely in V8 mode, preventing it from switching to V4 mode under light load conditions. However, some users have noted that even after disabling AFM, the vehicle's display may still show it switching between 8 and 4 cylinders, which can cause confusion about whether the feature is truly disabled. This may be a display issue rather than an operational one. You can use the link below to order while the part is in stock. Your order will come with a 30-day post-purchase price match guarantee. Enjoy shopping! https://www.carparts.com/tuner/diablo-sport/dbs8200?can=CPGG4850_CSQA_20240807

Hi Buford, thanks for initiating contact. This tuner cannot turn off or disable the TPMS system on vehicles. The TPMS system will remain active even after using the inTune tuner. If you're still interested in this tuner your vehicle information matches this product, use the link below to order while the part is in stock. Your order will come with a 30-day post-purchase price match guarantee. Enjoy shopping! https://www.carparts.com/tuner/diablo-sport/dbs8200?can=CPGG4850_CSQA_20240621

Hi Dave, thank you for reaching out. Yes, this will. You can use this link to order the part and take advantage of our low price for this item: https://www.carparts.com/power-programmer/diablo-sport/dbs8200?can=CPAP3648_CSQA_20240330 I hope this helps. Happy shopping.